Eu-Coordinated semiconducting polymer nanoparticles as a novel nanoprobe with two detection method signals for determination of copper(II) ions

Eu-coordinated semiconducting polymer nanoparticles (SPNs-Eu) were developed for bimodal analysis of copper(II) ions (Cu2+) over a wide dynamic range (μM to pM). In this sensing system, the first readout mode is based on fluorescence signal SPNs-Eu. A significant quenching fluorophore selective presence Cu2+ due aggregation The aggregations are caused by chelation with carboxylate groups SPNs-Eu and amount can be quantified 153Eu using single-particle inductively coupled plasma mass spectrometry (sp-ICPMS). This second these nanoparticles, which calibrated sub-pM determination Cu2+. Compared monodisperse reagent, in significantly decreases number detected particles or particle clusters within sampling period sp-ICPMS measurement. yields facile rapid detection method rather limited linear from 2 μM 50 limit (LOD) 0.29 μM. contrast, provides far more sensitive 1 pM 10 LOD 0.42 pM.